GLEN ALLEN, Mo. — A large tornado tore through southeastern Missouri before dawn on Wednesday,

killing at least five people as a broad swath of the Midwest and South kept a wary eye out for further storms 

The tornado touched down around 3:30 a.m.

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and moved through a rural area of Bollinger County, about 50 miles (80 kilometers) south of St. Louis, said Sgt. Clark Parrott of the Missouri State Highway Patrol.

rews from more than 20 agencies were on the scene 

and clearing debris in search of any others who might have been killed or injured,